An in-vitro Investigation of Iron-Containing Hydroxyapatite/Titanium Composites

Abstract

Abstract: The in-vitro biological behavior of a newly-developed iron-containing hydroxyapatite/titanium (HA/Ti) composite was investigated by immersing the composites in the simulated body fluid (SBF) for up to 5 weeks. The addition of iron was observed to have a significant influence on the in-vitro biological behavior of the composites. The obtained results revealed that the stability of the composites in the physiological solution was markedly improved. The solubility decreased in the order of pure HA, HA/5%(Ti-33%Fe), and HA/15%(Ti-33%Fe). Precipitation occurred on the surface of HA/5%(Ti-33%Fe) composite, showing a good combination of physiostability with bioactivity, while HA/15%(Ti-33%Fe) composite exhibited superior physiostability since there was no obvious change on the surface of HA/15%(Ti-33%Fe).

Key words: Hydroxyapatite composite, Iron, Titanium, Simulated body fluid, Biological behavior

Q. Chang, H.Q. Ru, D.L. Chen, X.Y. Yue, L. Yu, C.P. Zhang. An in-vitro Investigation of Iron-Containing Hydroxyapatite/Titanium Composites[J]. J Mater Sci Technol, 2011, 27(6): 546-552.

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