Abstract: A novel compliant spinal fixation designed based on the concept of compliant mechanisms can reduce the stress-shielding effect and adjacent segment degeneration (ASD) effectively, but propose higher requirements for the properties of the used materials. Bulk metallic glasses (BMGs), as a kind of young biomaterials, exhibiting excellent comprehensive properties, which are attractive for compliant spinal fixation. Here, according to the practical service condition of the basic elements in compliant spinal fixation, large deflection deformation behaviors of Zr₆₁Ti₂Cu₂₅Al₁₂ (at.%, ZT1) BMG beam, including elastic, yielding and plastic were investigated systematically. It was shown that the theoretical nonlinear analytical solution curve as the benchmark not only with the capacity to predict the nonlinear load-deflection relation within the elastic deformation regime, but also assists to capture the yielding event roughly, which can be used as a powerful design tool for engineers. To capture the beginning of the yielding event exactly, bending proof strength (σ_p,0.05%) accompanied with tiny permanent strain of 0.05% was proposed and determined for BMGs in biomedical implant applications, which is of significance for setting the allowable operating limits of the basic flexible elements. By approach of interrupted loading-unloading cycles, plastic deformation driven by the bending moment can be classified into two typical stages: the initial stage which mainly characterized by the nucleation and intense interaction of abundant shear bands when the plastic strain below the critical value, and the second stage which dominated by the progressive propagation of shear bands and coupled with the emergence of shear offsets on tensile side. The plasticity of BMG beam structures depends on the BMG's inherent plastic zone size (r_p). When the half beam thickness less than that of the r_p, the plastic deformation of BMGs will behave in a stable manner, which can be acted as the margin of safety effectively.

Key words: Metallic glasses, Biomaterials, Compliant spinal fixation, Large deflection deformation, Plastic deformation