J. Mater. Sci. Technol. ›› 2024, Vol. 179: 26-39.DOI: 10.1016/j.jmst.2023.08.056

• Research Article • Previous Articles     Next Articles

Influence of high temperature oxidation on mechanical properties and in vitro biocompatibility of WE43 magnesium alloy fabricated by laser powder b e d fusion

Jinge Liua,d, Shuyuan Minb,e, Zijun Maoa,d, Mengran Zhoud, Bingchuan Liub,e, Dazhi Liug, Fei Songc, Peng Wena,d, Yun Tianb,e, Yufeng Zhengf   

  1. aThe State Key Laboratory of Tribology in Advanced Equipment, Tsinghua University, Beijing 100084, China;
    bDepartment of Orthopaedics, Peking University Third Hospital, Beijing 100191, China;
    cInstitute for Precision Medicine Tsinghua University, Beijing Tsinghua Changgung Hospital, Beijing 102218, China;
    dDepartment of Mechanical Engineering, Tsinghua University, Beijing 100084, China;
    eEngineering Research Center of Bone and Joint Precision Medicine, Ministry of Education, Beijing 100191, China;
    fSchool of Materials Science and Engineering, Peking University, Beijing 100871, China;
    gTangshan Weihao Magnesium Powder Co., Ltd., Qian'an064406, China
  • Received:2023-05-16 Revised:2023-08-03 Accepted:2023-08-16 Published:2024-04-20 Online:2024-04-15
  • Contact: *E-mail addresses: wenpeng@tsinghua.edu.cn (P. Wen), tiany@bjmu.edu.cn (Y. Tian), yfzheng@pku.edu.cn (Y. Zheng).

Abstract: Laser powder bed fusion (L-PBF) has been used to fabricate biodegradable Mg implants of WE43 alloy, but the degradation is too fast compared with the term bone reconstruction. Previous studies show that high temperature oxidation (HTO) can successfully inhibit the degradation of WE43 alloy. In this work, the infiuence of HTO on L-PBF samples of WE43 alloy was investigated regarding tensile, compressive, and abrasive resistance, as well as in vitro cytotoxicity, cell proliferation, hemolysis, and osteogenesis. Compared with the as-built L-PBF samples, HTO increased grain size and grain texture, stabilized and coarsened precipitates, and caused discontinuous static recrystallization in the matrix. The oxide layer at the surface of the HTO samples improved surface roughness, hydrophilia, hardness, and abrasive resis-tance. The tensile strength decreased slightly from 292 to 265 MPa, while the elongation substantially increased from 10.97% to 16.58% after HTO. The in vitro cell viability, cell proliferation, hemolysis, and osteogenic effect were considerably enhanced due to the improvement of surface quality and the initial inhibition of excessive Mg2+ releasement. Overall, HTO is of great benefit to the surface performance, ductility, and biocompatibility of WE43 alloy fabricated by L-PBF for biodegradable applications.

Key words: Additive manufacturing, Biodegradable metal, Magnesium alloy, WE43, High temperature oxidation