Effect of Elastic Modulus on Biomechanical Properties of Lumbar Interbody Fusion Cage

J Mater Sci Technol ›› 2009, Vol. 25 ›› Issue (03): 325-328.

• Research Articles • Previous Articles Next Articles

Effect of Elastic Modulus on Biomechanical Properties of Lumbar Interbody Fusion Cage

Yue Zhu^1)†, Fusheng Li²⁾, Shujun Li³⁾, Yulin Hao³⁾ and Rui Yang³⁾

1) Department of Orthopaedics, the First A±liated Hospital of China Medical University, Shenyang 110001, China
2) Department of Bone Tumor, The People0s Hospital of Liaoning Province, Shenyang 110016, China
3) Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China

Received:2008-04-11 Revised:2008-04-25 Online:2009-05-28 Published:2009-10-10
Contact: Yue Zhu

Abstract

Abstract:

This work focuses on the influence of elastic modulus on biomechanical properties of lumbar interbody fusion cages by selecting two titanium alloys with different elastic modulus. They were made by a new β type alloy with chemical composition of Ti-24Nb-4Zr-7.6Sn having low Young0s modulus ~50 GPa and by a conventional
biomedical alloy Ti-6Al-4V having Young0s modulus »110 GPa. The results showed that the designed cages with low modulus (LMC) and high modulus (HMC) can keep identical compression load ~9.8 kN and endure fatigue cycles higher than 5×10⁶ without functional or mechanical failure under 2.0 kN axial compression. The
anti-subsidence ability of both group cages were examined by axial compression of thoracic spine specimens (T₉~T₁₀) dissected freshly from the calf with averaged age of 6 months. The results showed that the LMC has better anti-subsidence ability than the HMC (p<0.05). The above results suggest that the cage with low elastic modulus has great potential for clinical applications.

Key words: Titanium alloy; Lumbar; Interbody fusion cage; Biomechanics

Yue Zhu,Fusheng Li,Shujun Li,Yulin Hao,Rui Yang. Effect of Elastic Modulus on Biomechanical Properties of Lumbar Interbody Fusion Cage[J]. J Mater Sci Technol, 2009, 25(03): 325-328.

References

[1 ] Y. Arai, M. Takahashi and H. Kurosawa: J. Orthop. Sur., 2002, 10(1), 1.
[2 ] P.C. McAfee , J.G. DeVine,C.D. Chaput,B.G. Prybis,I.L. Fedder, B.W. Cunningham, D.J. Farrell, S.J. Hess and F.E. Vigna: Spine, 2005, 30(6 Suppl), S60.
[3 ] T.A. Zdeblick and F.M. Phillips: Spine, 2003, 28(15 Suppl), S2.
[4 ] N. Desogus, F. Ennas, R. Leuze and A. Maleci: J. Neurosurg Sci., 2005, 49(4), 137.
[5 ] P.C. McAfee: J. Bone Joint Surg (Am), 1999, 81, 859.
[6 ] T. Ste®en, A. Tsantrizos, I. Fruth and M. Aebi: J. Eur. Spine, 2000, 9(Suppl 1),, S89.
[7 ] J. Beddoes and K. Bucci: J. Mater. Sci., Mater. Med., 1999, 10, 389.
[8 ] S.H. Lee, F.R. Brennan, J.J. Jacob, R.M. Urban, D.R. Ragasa and T.T.Glant: J. Orthop. Res., 1997, 15, 40.
[9 ] K. Merritt and S.A. Brown: Clin. Orthop. Relat. Res., 1996, 329, 233.
[10] T.H. Smit, R.MÄuller, D.M. Van and P.I. Wuisman: Spine, 2003, 28(16), 1802.
[11] ASTM F 2077-03, Test Methods For Intervertebral Body Fusion Devices1. ASTM Committee F04 on Medical and Surgical Materials and Devices and is the direct responsibility of Subcommittee F04.25 on Spinal Devices.
[12] ASTM F2267-04. Standard test method for measuring load induced subsidence of intervertebral body fusion device under static axial compression. Committee F04
on Medical and Surgical Materials and Devices, developed by Subcommittee F04.25.
[13] S.D. Kuslich, C.L. Ulstrom, S.L. Gri±th, J.W. Ahern and J.D. Dowdle: Spine, 1998, 23(11), 1267.
[14] D.S. Brodke, J.C. Dick, D.N. Kuni, R. McCabe and T.A. Zdeblick: Spine, 1997, 22(1), 26.
[15] N. Kumar, M.R. Judith, A. Kumar, V. Mishra and M.C. RobertMC: Spine, 2005, 30(15), 1731.
[16] Nachemson and J.M. Morris: J. Bone Joint Surg. Am., 1964, 46, 1077.
[17] K.U. Lewandrowski, M.V. Cattaneo, J.D. Gresser, D.L. Wise, R.L. White, L. Bonassar and D.J. Trantolo: Tissue Eng., 1999, 5(4), 305.
[18] H. Wilke, P. Neef, B. Hinz, H. Seidel and L. Claes: Clin. Biomech., 2001, 16, 111.
[19] M. Krammer, R.Dietl, C.B. LumentaA. Kettler, H.J. Wilke, A. BÄuttner and L. Claes: Acta Neurochir., 2001, 143, 1217.
[20] J.Y. Choi and K.H. Sung: Eur. Spine, 2006, 15(1), 16.

Effect of Elastic Modulus on Biomechanical Properties of Lumbar Interbody Fusion Cage

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 0

Recommended Articles

Metrics

Comments