Anti-fatigue ionic gels for long-term multimodal respiratory abnormality monitoring

doi:10.1016/j.jmst.2022.12.031

J. Mater. Sci. Technol. ›› 2023, Vol. 151: 99-108.DOI: 10.1016/j.jmst.2022.12.031

• Research Article • Previous Articles Next Articles

Anti-fatigue ionic gels for long-term multimodal respiratory abnormality monitoring

Xiang-Jun Zha^a,c,1, Jian-Bo Li^b,1, Guo-Peng Liang^b, Jun-Hong Pu^a, Zhong-Wei Zhang^b, Bo Wang^b, Ji-Gang Huang^e, Jin Jia^a, Xin Zhao^a, Kai-Qi Pan^d, Mei-Ling Dong^b, Kai Ke^a, Yan Kang^b,*, Wei Yang^a,*

^aCollege of Polymer Science and Engineering, Sichuan University, State Key Laboratory of Polymer Materials Engineering, Chengdu 610065, Sichuan, China;
^bDepartment of Critical Care Medicine, West China Hospital, Sichuan University, 37 Guo Xue Xiang St, Chengdu 610041, Sichuan, China;
^cLaboratory of Liver Transplantation, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China;
^dCentre for Advanced Macromolecular Design and Australian Centre for NanoMedicine, School of Chemical Engineering, UNSW Sydney, NSW 2052, Australia;
^eSchool of Mechanical Engineering, Sichuan University, Chengdu 610065, Sichuan, China

Received:2022-08-27 Revised:2022-11-28 Accepted:2022-12-14 Published:2023-07-10 Online:2023-02-16
Contact: * E-mail addresses: kangyan@scu.edu.cn (Y. Kang), weiyang@scu.edu.cn (W. Yang).
About author:¹ These authors contributed equally to this work.

Abstract

Abstract: Wearable electronics integrated with stretchable sensors are considered a promising and non-invasive strategy to monitor respiratory status for health assessment. However, long-term and stable monitoring of respiratory abnormality is still a grand challenge. Here, we report a facile one-step thermal stretching strategy to fabricate an anti-fatigue ionic gel (AIG) sensor with high fatigue threshold (Γ₀ = 1130 J m^-2), high stability (> 20,000 cycles), high linear sensitivity, and recyclability. A multimodal wearable respiratory monitoring system (WRMS) developed with AIG sensors can continuously measure respiratory abnormality (single-sensor mode) and compliance (multi-sensor mode) by monitoring the movement of the ribcage and abdomen in a long-term manner. For single-sensor mode, the respiratory frequency (F_r), respiratory energy (E_r), and inspire/expire time (I/E ratio) can be extracted to evaluate the respiratory status during sitting, sporting, and sleeping. Further, the multi-sensors mode is developed to evaluate patient-ventilator asynchrony through validated clinical criteria by monitoring the incongruous movement of the chest and abdomen, which shows great potential for both daily home care and clinical applications.

Key words: Anti-fatigue ionic gels, Wearable electronics, Multimodal respiratory monitoring

Xiang-Jun Zha, Jian-Bo Li, Guo-Peng Liang, Jun-Hong Pu, Zhong-Wei Zhang, Bo Wang, Ji-Gang Huang, Jin Jia, Xin Zhao, Kai-Qi Pan, Mei-Ling Dong, Kai Ke, Yan Kang, Wei Yang. Anti-fatigue ionic gels for long-term multimodal respiratory abnormality monitoring[J]. J. Mater. Sci. Technol., 2023, 151: 99-108.

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Anti-fatigue ionic gels for long-term multimodal respiratory abnormality monitoring

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