Electrospinning nanofiber scaffolds for soft and hard tissue regeneration

Xianrui Xie^a, Yujie Chen^a^,^*, Xiaoyu Wang^a, Xiaoqing Xu^a, Yihong Shen^a, Atta ur Rehman Khan^a, Ali Aldalbahi^b^,^*(

), Allison E. Fetz^c, Gary L. Bowlin^c, Mohamed El-Newehy^b, Xiumei Mo^a^,^*(

)

Fig. 7.. Schematic of the fabrication of a scaffold for skin tissue engineering by a four-step process and the animal experiment to evaluate wound repair [44]. (1) 2D nanofibrous mats were fabricated via electrospinning. (2) A homogeneous short fiber solution was prepared by high-speed mechanical cutting. (3) The 3D scaffold was obtained after freeze-drying the solution. (4) The 3D scaffold was reinforced through heat treatment.