Abstract: Amino acid functionalized calixarenes, incorporating aspartic acid 1, alanine 2, and sarcosine 3, have been synthesized and studied as crystal growth modifiers. Calixarene 1 was found to alter the morphology of calcite significantly, elongating crystals in the c direction, and inducing chiral morphologies and growth features on the crystal surface. Additive 2, a secondary amide, was more efficacious than tertiary amide 3, suggesting a role for hydrogen bonding of the amide proton in crystal growth modification...

Key words: Calixarene, Crystal growth, Calcium carbonate...