J Mater Sci Technol ›› 2004, Vol. 20 ›› Issue (06): 772-774.

• Research Articles • Previous Articles     Next Articles

Formation and Characterization of Bone-like Nanoscale Hydroxyapatite in Glass Bone Cement

Qiang FU, Nai ZHOU, Wenhai HUANG, Deping WANG, Liying ZHANG   

  1. School of Materials Science and Engineering, Tongji University, Shanghai 200092, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2004-11-28 Published:2009-10-10
  • Contact: Wenhai HUANG

Abstract: Glass based bone cement (GBC) was synthesized by mixing CaO-SiO¬2-P¬2O¬5 based glass powder with ammonium phosphate liquid medium. Bone-like hydroxyapatite (HAP, Ca¬10(PO¬4)¬6(OH¬2) was found to form after GBC was immersed in simulated body fluid (SBF). HAP crystal grew with an increasing time along c axle and reached about 200 nm in length after 30~days, however, the end plane granularity remained 30~50 nm. The chemical composition, crystal structure and morphology of HAP formed from GBC were proved to have great resemblance with living HAP. It is believed that GBC was a desirable biomedical material with high bioactivity. Furthermore, the high compressive strength guaranteed the possibility of GBC in clinical application.

Key words: Bioactivity, Bone cement, Hydroxyapatite, Microstructure