Synthesis and Reinforcement Effects on Bioglass Bone Cement of Chitosan-Hydroxyapatite Composites

J. Mater. Sci. Technol. ›› 2009, Vol. 25 ›› Issue (04): 551-555.

Synthesis and Reinforcement Effects on Bioglass Bone Cement of Chitosan-Hydroxyapatite Composites

LIU Jing-Xiao¹;Shi Fei¹;YU Ling¹;NIU Li-Ting²;GAO Shan-Shan²

1. Dalian Polytechnic University
2.

收稿日期:2008-05-26 修回日期:2008-11-20 出版日期:2009-07-28 发布日期:2009-10-10
通讯作者: LIU Jing-Xiao
基金资助:
辽宁省博士启动基金项目；辽宁省教育厅A类攻关项目;辽宁省博士启动基金项目；辽宁省教育厅A类攻关项目

Synthesis of Chitosan-Hydroxyapatite Composites and Its Effect on the Properties of Bioglass Bone Cement

Jingxiao Liu^†, Fei Shi, Ling Yu, Liting Niu, Shanshan Gao

School of Chemical Engineering and Materials, Dalian Polytechnic University, Dalian 116034, China

Received:2008-05-26 Revised:2008-11-20 Online:2009-07-28 Published:2009-10-10
Contact: Jingxiao Liu
Supported by:
the Liaoning Province Doctoral Startup Foundation, China (No. 20021054)
the Liaoning Province Ministry Project of Education, China (No. 202073425)

摘要/Abstract

Abstract:

Chitosan-hydroxyapatite (CS-HA) composite powders were synthesized via in situ co-precipitation method, through the reaction of Ca(NO₃)₂and H₃PO₄ in the simulated body fluid (SBF) containing appropriate amount of chitosan. The thermal evolution, microstructure and morphology were studied by TG-DTA (thermogravimetry-differential thermal analysis), XRD (X-ray diffraction), FTIR (Fourier transform infrared spectroscopy) and TEM (transmission electron microscopy). The in vitro bioactivity test showed that the obtained CS-HA composites had higher capability of inducing calcium ions deposition. Effects of CS-HA composites on the bioactivity and compressive strength of bioglass bone cement were investigated. The results indicated that the bioactivity of bioglass bone cement could be improved further when CS-HA composite powders were added into the cement, and appropriate amount of CS-HA additive was favorable for compressive strength improvement of bioglass bone cement.

Key words: Hydroxyapatite, Chitosan, Composites, Bone cement

LIU Jing-Xiao Shi Fei YU Ling NIU Li-Ting GAO Shan-Shan. Synthesis and Reinforcement Effects on Bioglass Bone Cement of Chitosan-Hydroxyapatite Composites[J]. J. Mater. Sci. Technol., 2009, 25(04): 551-555.

Jingxiao Liu,Fei Shi,Ling Yu,Liting Niu,Shanshan Gao. Synthesis of Chitosan-Hydroxyapatite Composites and Its Effect on the Properties of Bioglass Bone Cement[J]. J Mater Sci Technol, 2009, 25(04): 551-555.

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